Richard Neutze

Reflections on emerging possibilities in Life-science using tender X-rays
Presenter Richard Neutze, University of Gothenburg, Sweden
Session Title Science Opportunities at SLAC in the Tender X-ray Range (2-5 keV)
Abstract

X-ray free electron laser (XFEL) radiation is revolutionizing experimental approaches to structural biology. The potential scientific impact of FEL radiation in the tender X-ray regime is less clear since diffraction studies are not practicable to 2 Å resolution. Here I will offer speculative ideas as to where tender XFEL radiation may be expected to have future impact within life science. Emphasis will be given to where the LCLS-II may offer strategic advantages for classes of experiments that may benefit from the high repetition rate due to the need to extract very small structural signals; or due to the ability to control the time-structure of XFEL pulses. My presentation will focus on the potential for completely novel discoveries using time-resolved dynamical studies. To illustrate the type of scientific questions that may emerge I will suggest combining time-resolved wide angle X-ray scattering, time-resolved X-ray spectroscopy, and time resolved X-ray imaging or holography. To stimulate discussion this presentation will emphasize ideas for the future rather than experimental results to date.