LOCATION: All events will take place at SUSB (Building 53) unless otherwise noted in the program booklet.
Scientific Program (PDF): Download the BSR 2016 Scientific Program here.
BSR Abstract Booklet (PDF): Download the BSR 2016 Abstract Booklet here.
List of Posters (Presentation Order; PDF): Download the BSR 2016 Poster Session list here (presentation order).
List of Posters (Alphabetical Order; PDF): Download the BSR 2016 Poster Session list here (alphabetical order).
Sunday, August 21, 2016 | ||
Arrival and Registration | 15:00-17:00 | |
Reception | 17:00-19:00 | |
Monday, August 22, 2016 | ||
Soichi Wakatsuki, Stephen Burley, Mike Dunne, Kelly Gaffney, and Henry van den Bedem | Welcome | 08:15-08:30 |
Membrane Proteins (Chair: Poul Nissen) | ||
Poul Nissen, Aarhus University | Introduction | 08:30-08:35 |
Zhi-Jie Liu, iHuman Institute |
Structural and functional studies of Human GPCRs |
08:35-08:55 |
Brian Kobilka, Stanford University | The dynamic process of G protein activation | 08:55-09:15 |
Irmgard Sinning, Heidelberg University | Regulation of protein targeting: when SRP meets the ribosome | 09:15-09:35 |
Jian-Ren Shen, Okayama University | High resolution structure of photosystem II and the mechanism of photosynthetic water-splitting | 09:35-09:55 |
Liz Carpenter, University of Oxford | Structure and function of K2P ion channels from synchrotron data from Diamond and serial femtosecond crystallography at LCLS | 09:55-10:15 |
Alexander Kintzer, UCSF | Structure, inhibition, and regulation of a two-pore channel TPC1 |
10:15-10:30 |
Break / Group Photo | 10:30-11:00 | |
Macromolecular Complexes (Chair: Bill Weis) | ||
Bill Weis, Stanford University | Introduction | 11:00-11:05 |
Osamu Nureki, University of Tokyo | Structure-based development of genome-editing tool, CRISPR-Cas9 towards medical applications | 11:05-11:25 |
Richard Garratt, University of São Paulo | Septins, a molecular jigsaw | 11:25-11:45 |
Yvonne Jones, University of Oxford | Cell surface signaling systems, structural insights in developmental biology | 11:45-12:05 |
Jim Hurley, UC Berkeley | 12:05-12:25 | |
Natalie Strynadka, University of British Columbia |
Structure-based piecing together of the Type III secretion system puzzle |
12:25-12:45 |
Karthik Sathiyamoorthy, Stanford University | Structural Basis for Epstein-Barr Virus Host Cell Tropism mediated by gp42 and gHgL Entry Glycoproteins | 12:45-13:00 |
Lunch Break/Poster Setup | 13:00-14:30 | |
Poster Session 1 | 14:30-16:00 | |
Hybrid Methods (Chair: Robert McKenna) | ||
Robert McKenna, University of Florida | Introduction | 16:00-16:10 |
Gabriel Waksman, University College London/Birkbeck | Structural and Molecular Biology of Bacterial Secretion Systems | 16:10-16:30 |
Jill Trewhella, University of Sydney | Small-Angle Scattering: an Effective Constraint in Modelling Complex Biomolecular Structures | 16:30-16:50 |
Mike Hough, University of Essex |
Fingerprinting Redox and Ligand States in Protein Crystals: Applications for Validation and Determining Structural Movies |
16:50-17:10 |
Flora Meilleur, Oak Ridge National Laboratory | Radiation damage free structural studies of cellulolytic redox enzymes using neutron scattering and diffraction | 17:10-17:30 |
Martin Beck, EMBL Heidelberg | In situ structural analysis of the human nuclear pore complex | 17:30-17:50 |
Hélène Déméné, CNRS | Towards a Mechanistic Understanding of the Opioid Mu Receptor Activation | 17:50-18:10 |
Orion Shih, NSRRC | Linear Oligomerization Process of BAX Revealed from Coexisting Intermediates in Solution | 18:10-18:30 |
Tuesday, August 23, 2016 | ||
Bioinformatics and Computing (Chair: Helen Berman) | ||
Helen Berman, Rutgers University - Introduction | Introduction | 08:30-08:35 |
Michael Levitt, Stanford University School of Medicine | Combinatorial methods solve a difficult structural problem to reveal how chaperonins work in eukaryotes | 08:35-08:55 |
Christine Orengo, University College London | CATH-FunFams: New domain families to explore protein structure and function space | 08:55-09:15 |
Paul Adams, Lawrence Berkeley National Laboratory | New methods for low resolution structure refinement | 09:15-09:35 |
Dan Rigden, University of Liverpool | Exploiting structural bioinformatics for unconventional molecular replacement | 09:35-09:55 |
Wladek Minor, University of Virginia |
High throughput computing on high output synchrotron facilities |
09:55-10:15 |
Daniel Franke, EMBL-Hamburg | Rapid Shape Classification of Biological Macromolecules from Small Angle X-ray Scattering Data |
10:15-10:30 |
Break | 10:30-11:00 | |
Science with Upgraded SRS (Chair: Stefan Vogt) | ||
Stefan Vogt, Argonne National Laboratory | Introduction | 11:00-11:10 |
Pieter Glatzel, ESRF | Hard X-ray photon-in/photon-out spectroscopy at ESRF-EBS | 11:10-11:30 |
Marjolein Thunnissen, MAX IV Laboratory |
Possibilities for the Life Sciences at the first diffraction limited light-source MAX IV |
11:30-11:50 |
Gayle Woloschak, Northwestern University |
Upgrading X-ray fluorescence imaging |
11:50-12:10 |
Lin Yang, Brookhaven National Laboratory | The Life Science X-ray Scattering (LiX) Beamline at NSLS-II | 12:10-12:30 |
Lunch Break/Poster Setup | 12:30-14:00 | |
Poster Session 2 | 14:00-15:30 | |
Industrial or Pharmaceutical Applications (Chair: Nigel Walker) | ||
Nigel Walker, Molecular Consulting - Introduction | The application of structural biology to pharmaceutical drug discovery | 16:00-16:10 |
Benjamin Bax, GlaxoSmithKline, UK | How is movement coupled to catalysis in DNA gyrase? | 16:10-16:30 |
Chun-Wa Chung, GlaxoSmithKline R&D, UK | How crystallography can (and can’t) help us find drugs | 16:30-16:50 |
Avni Bhatt, University of Florida | Crystallographic insight into enhanced catalytic activity of carbonic anhydrase II using “activating” ligands | 16:50-17:10 |
SLAC Tour - Pre-registration required | 17:10-19:00 | |
BBQ - Pre-registration required | 19:00-22:00 | |
Wednesday, August 24, 2016 | ||
X-ray/IR Imaging/SR-CDI (Chair: Chris Jacobsen) | ||
Chris Jacobsen, Argonne National Laboratory | Introduction | 08:30-08:35 |
Tanja Dučić, CELLS-ALBA | Multimodal synchrotron spectro-microscopy for elucidation cellular disorders in neuro-degenerative diseases | 08:35-08:55 |
Liz Duke, Diamond Light Source | Cryo Soft X-ray Microscopy: New Opportunities for Structural Biology | 08:55-09:15 |
Patrick La Riviere, University of Chicago | Development of “color” x-ray histology using multiple metal stains and multi-energy synchrotron CT | 09:15-09:35 |
Andreas Menzel, Paul Scherrer Institute | Bio-Imaging using X-Ray Ptychography - The Method, Recent Advances, and Applications | 09:35-09:55 |
Carol Hirschmugl, University of Wisconsin - Milwaukee | Rapid 2D and 3D IR imaging Applied to Biologically and Chemically Complex Systems | 09:55-10:15 |
Michael Martin, LBNL | Biological SINS: Broadband synchrotron infrared nano-spectroscopy of biological materials | 10:15-10:30 |
Break | 10:30-11:00 | |
Dynamics (Chair: Keith Moffat) | ||
Keith Moffat, University of Chicago | Introduction | 11:00-11:05 |
Marius Schmidt, University of Wisconsin - Milwaukee |
Ultrafast Dynamics in Proteins Investigated by Time-Resolved Serial Femtosecond Crystallography |
11:05-11:25 |
Lois Pollack, Cornell University | Time-resolved studies: SAXS of protein-DNA complexes and mixing jets for XFELs | 11:25-11:45 |
Rajmund Mokso, MAX IV Laboratory | Fast tomographic microscopy to capture the dynamics of life | 11:45-12:05 |
Doeke Hekstra, UT Southwestern | Probing the mechanics of molecular machines with electric fields and X-rays | 12:05-12:25 |
James Fraser, UC San Francisco |
Birth of the Cool: Multitemperature Multiconformer X-Ray Crystallography |
12:25-12:45 |
Daniel Keedy, UCSF | Multitemperature synchrotron crystallography and ligand scanning reveal novel allosteric modulators of the therapeutic target PTP1B | 12:45-13:00 |
Lunch Break/Poster Setup | 13:00-14:30 | |
Poster Session 3 | 14:30-16:00 | |
7 Years of XFEL in Structural Biology (Chair: Janet Smith) | ||
Janet Smith, University of Michigan | Introduction | 16:00-16:10 |
Richard Neutze, University of Gothenburg |
Time-Resolved serial femtosecond crystallography studies of bacteriorhodopsin - a light-driven proton pump. |
16:10-16:30 |
Ilme Schlichting, Max Planck Institute for Medical Research |
Phasing Serial Femtosecond Crystallography data |
16:30-16:50 |
Henry Chapman, DESY | Macromolecular Diffractive Imaging using Disordered Crystals | 16:50-17:10 |
Axel Brunger, Stanford University | XFEL crystal structure of the Synaptotagmin-1 : SNARE complex | 17:10-17:30 |
So Iwata, RIKEN SPring-8 Center/Kyoto University |
Macromolecular Crystallography at SACLA |
17:30-17:50 |
Andy Aquila, SLAC National Accelerator Laboratory | Single Particle Imaging at the Linac Coherent Light Source | 17:50-18:10 |
Jan Kern, LBNL | Mechanism of Water Oxidation in Photosystem II Studied by Room Temperature fs X-ray Crystallography and Spectroscopy | 18:10-18:30 |
Soichi Wakatsuki and Stephen Burley | Closing Remarks | 18:30-19:00 |